Selective inhibitor of cGMP-specific PDE5, which is responsible for the breakdown of cGMP in the cavernous body of penis. Actively enhances the relaxing effect of nitric oxide on smooth muscle of the cavernous body and increases blood flow to the penis. When you activate the NO-cGMP chain, observed during sexual arousal, inhibition of PDE5 increases cGMP in the cavernous body. Pharmacological effect is achieved only in the presence of sexual stimulation. Activity against PDE5 in 10-10000 times higher activity against PDE isoenzymes, etc. (1, 2, 3, 4, 6). Indications:

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Description of the active substance (INN)
Sildenafil
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coated tablets
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